|The Estrogen Metabolism Assessment is a hormone test which evaluates
how estrogen is being processed in
the body and if the bad estrogens are
being built up which may lead to cancer, both breast and prostate, osteoporosis, heart disease and autoimmune disorders.
This test by Genova Diagnostics yields
into many estrogen-dependent conditions
and provide important tools for monitoring
dietary, lifestyle and hormone therapies.
This test reveals important clinical information about:
Estrogen metabolism in premenopausal and postmenopausal women, focusing
on the critical balance between the body's two primary hydroxyestrogens
(active and inactive)
- Hormonal imbalances that may affect the risk and prognosis of
estrogen-dependent health conditions, such as breast cancer, lupus,
osteoporosis, and heart disease.
physiological impact of hormone therapy-including dietary, nutritional,
lifestyle, and estrogen replacement interventions.
To order this
test click ADD
The potential impact of estrogen metabolism on a personal health and well-being is enormous.Estrogen can exert a strong influence in diverse conditions such as:
- Breast cancer
- Prostate cancer
- Heart disease
- Autoimmune disorders
Recent scientific advances into estrogen metabolism have shed new light on more effective clinical interventions in estrogen-dependent conditions.
Estrogen metabolites provide valuable clinical information regarding cancer risk.Â Two significant metabolites that can be accurately assessed are 16 alpha-hydroxyestrone (16 alpha-OHE1) and 2-hydroxyestrone (2-OHE1).
- 16 alpha-OHE1 is a powerful metabolite that stimulates target tissues.Â Levels can rise in response to obesity, alcohol consumption, and toxic exposure.Â High levels of this potent metabolite are linked to increased risk and poorer prognosis in conditions linked to estrogen excess such as breast cancer and lupus.
- 2-OHE1 is a metabolite that binds weakly to cell receptors and may slow cell proliferation.Â Excessive levels of 2-OHE1 may increase the risk of osteoporosis in post-menopausal women with low estrogen.
The ration between 2-OHE1 and 16 alpha-OHE1 is the key to optimizing health.Â Treatments that increase the 2:16 alpha-OHE1 ratio help to reduce the risk of estrogen-dependent disease.Â Using the assessment, practitioners can monitor the impact of dietary intervention (flaxseed, soy products, cruciferous vegetables or derivatives like indole-3-carbinol and diindolylmethane, omega-3 fatty acids) and exercise. The ratio also allows for accurate monitoring of clinical safety and effectiveness of hormone replacement therapy (HRT).
The Estrogen Metabolism Assessmentis designed for both premenopausal and postmenopausal women. It can be performed using serum or urine. Serum sampling provides a direct assessment of circulating estrogen metabolites. Urine testing offers convenient, noninvasive sample collection.
balance between 2-OHE1 and 16alpha-OHE1 is the key to optimal health.
Measuring these primary estrogen metabolites allows practitioners
to develop individualized therapy based on each woman's unique health
(lignans), soy products (isoflavones), cruciferous vegetables (indole-3-carbinol),
vigorous exercise, and omega-3 fatty acids are interventions that
may reduce the risk of estrogen-dependent disease by favorably modifying
the 2:16alpha-OHE1 ratio. Using this assessment, practitioners can
monitor the physiological impact of these and other treatments (including
hormone replacement therapy), gaining added insight into their clinical
safety and effectiveness.
Estrogen Metabolism Assessment is designed for both premenopausal
and postmenopausal women. It can be performed using serum or urine.
Both tests are fully validated and approved for in vitro diagnostic
use by the FDA. Serum sampling provides a direct assessment of circulating
estrogen metabolites able to act directly on target tissues. Urine
testing offers convenient, noninvasive sample collection. In both
serum and urine, 2-OHE1 is the primary 2-hydroxyestrogen measured,
although urinary analysis also detects small amounts of other 2-hydroxyestrogens.
It is recommended that baseline and follow-up analysis be performed
using the same specimen type.
lab tests can be done through the mail in the privacy of your own
home, except blood tests, we send you to a lab to have your blood
drawn for these. After you pay for the test we mail you the kit,
the results take two weeks, the test results will be mailed to us
and we will call you to go over the results, its that easy! All
tests include the consultation for the report of findings.
Click on test of interest on the right for more information.
Call our office for details.
800-956-7083 OR 818-707-3126.