Male Hormone Panel™ (MHP™)
by Diagnos Tech allows the clinician
to assess male hormone functionality
affecting vigor, vitality and virility
using a non-invasive saliva collection.
The aging process is inevitable, but
restoring lost male vitality is within
reach. The Male Hormone Panel™ (MHP™)
evaluates the androgen pathway by measuring
the free fractions of 6 hormones: Androstenedione,
Testosterone (T), Dihydrotestosterone
(DHT), Estrone (E1), Progesterone (P),
To order this
test click ADD
Male Hormone Panel™ (eMHP™)
contains all the tests in the MHP™ plus
FSH and LH.
To order this test
There is growing awareness that
hormone function plays a vital role in a man's health over the course
of his lifetime. In particular, changes in the production of the sex
hormone testosterone can exert a profound influence on sexual function,
bone density, fat metabolism, mood states, energy levels, and even
physical appearance (skin and muscle tone).
Male Hormone Panel is an accurate, convenient, non-invasive saliva
assay that evaluates testosterone activity in men. This profile
can uncover disrupted testosterone secretion rhythms caused by aging,
chronic illness, infection, toxic exposure, smoking, trauma, and
many other factors. The test is indicated for sex related dysfunctions
such as low libido, impotence and hypogonadism, and for use in anti-aging
treatment programs that address possible hormonal imbalances behind
increasing fatigue, depression, and weight gain in middle-aged and
The aging process is inevitable. However, restoring lost male vitality
is within reach. The hormones involved in this restoration can now
be collectively measured in one salivary panel using the Regular
or Expanded Male Hormone Panels™ (MHP™& eMHP™).
The clinical problems that concern men the most can be grouped into
three general categories as listed below.
of Aging Men
loss of sense of well being
alteration in behavioral patterns
irritability & nervousness
change in sleep habits / insomnia
decline in sexual function & interest, diminished libido &
decrease in bone mass (osteoporosis)
decrease in muscle mass & strength
decrease in hair density
reduction in masculinity
Men of the "boomer" generation
not only desire, but actually expect
to have a longer life span than previous
generations. They also expect to maintain
youthful vitality and vigor into their
later years. However, due to lifestyle
choices and other factors, many men
will be disappointed, as their male
hormone production slowly declines.
At around puberty,
the important male hormone, testosterone reaches adult levels. For
a long time it was believed that men maintain adequate levels of
testosterone throughout life. Many men in their ?fties or older
however, experience a progressive decline in their energy, vitality,
sexual performance and mental capacity. This decline has been labeled
"Andropause." The causes of andropause are believed to
be a reduction in testosterone and other androgens. The testicles
show a progressive annual drop of 1-1.5% in testosterone output
after age 30. Furthermore, as men age, a 1-2% annual decline in
the free-fraction of testosterone and a progressive annual increase
of 1-2% in both Luteinizing Hormone (LH) and Follicle Stimulating
Hormone (FSH) has been documented. The clinical manifestations of
andropause usually lag ten to twenty years behind the onset of hormone
decline. Statistically, andropause affects at least 40% of men aged
55 - 65, and up to 80% of those aged 65 years or more.
levels of 6-8 hormones measured in the Male Hormone Panels,™
helps you formulate an effective plan to relieve andropausal symptoms.
is a precursor to all androgens and is a physiologic modulator of
DHEA & DHEA-S, the main adrenal androgens are the precursors
to both testosterone and estradiol, and the limiting factor in their
production especially under stress.
Androstenedione, another adrenal androgen and precursor to estrone
is freely inter-convertible with testosterone.
Estrone is the major estrogen in men and is the product of peripheral
aromatization of androstenedione in fat and muscle tissue.
Testosterone, the dominant testicular androgen, is the precursor
to 5-dihydrotestosterone (DHT). The androgenic effect in various
tissues is not exerted by testosterone but by the locally produced
Expanded MHP™ (eMHP™)
This panel includes all the 6 tests in the regular MHP,™ plus
FSH and LH. Salivary quantitation of FSH and LH is a technological
breakthrough that separates Diagnos-Techs from the crowd of copycat
laboratories. Testosterone and sperm production in males are the
equivalent of estrogen and ovulation in females. The pituitary neurohormones,
FSH and LH, stimulate and regulate spermatogenesis and testosterone
of an increase in FSH and LH levels is indicative of a progressive
decline in male sexuality and functionality. The clinical utility
of the Male Hormone Panels™ is shown below.
Measuring baseline hormones
Diagnosing andropause & hypogonadism
Therapeutic monitoring of HRT
Balancing of hormones
Investigating prostate hypertrophy, thinning of hair & hirsutism
Evaluating low-libido in both sexes
Male Hormone Therapy
Following the use of MHP™/eMHP,™ treatment plans using
hormones to replace and balance endogenous production usually produce
several positive effects:
Increase of fitness and sense of well-being
Decrease of body fat and increase in lean body mass
Resolution of hormone dependent libido problems
Prevention of hair thinning
Increase in hematocrit and RBC counts
Mitigation of osteoporosis and stimulation of bone formation
Decrease in total cholesterol, increase HDL
Note: Unmonitored male HRT may account for increased incidence of
prostatic complications, liver cancer, and accelerated atherosclerosis.
DHEA production by the adrenals normally decreases with age.
Reality: DHEA levels in healthy adult males are comparable at any
age and only fall as a result of stress-related adrenal exhaustion.
Radioimmunoassay (RIA) is the standard for testosterone testing.
Reality: The testosterone free fraction represents less than 2%
of the total hormone. At this low level (Pico-gram) RIA fails to
accurately detect testosterone and yields an underestimate of bio-available
hormone. This is true for both serum and saliva free fraction testing
Mith:Testosterone supplementation is
detrimental to the liver and lipid
Reality: This only applies to overdosed synthetic testosterone variants
that produce supra-physiologic androgenic activity. Monitoring and
adjusting natural testosterone intake to maintain physiologic levels,
actually improves the lipid pro?le and does not increase LDL, or
negatively impact the liver.
Injectable testosterone is best for male hormone replacement therapy.
Reality: Intramuscular testosterone injections abolish the circadian
rhythm and result in aggressive behavior. The rapid and uncontrolled
hormone absorption causes signi?cant swings in mood and sex drive.
Giving more testosterone will not remedy these swings.
A 58 yr. old man had been suffering for over 9 months with progressive
fatigue and lack of interest in sexual relations. His wife was worried
about him missing his weekly golf game. An e-MHP™ saliva panel
was done and it revealed:
Low normal (age adjusted)
FSH Moderately elevated
DHEA, DHT, Progesterone
and Estrone were normal
This case study illustrates the subtle and progressive nature of
andropause. While the testosterone level was normal, it was maintained
at the expense of a higher Pituitary LH stimulation and an increase
in demand for adrenal androstenedione. Mild declines in testicular
testosterone production prompt the adrenals to produce more androstenedione
to compensate for the lagging testicular performance.
Patient was started on a low dose of natural micronized testosterone
capsules and was back gol?ng in 3 weeks.
Clinics that use DHEA or androstenedione
to boost testosterone levels should
conduct follow up tests to insure
these hormones are not over-spilling
into the estrogen pathway.
All lab tests can be done through the mail in the privacy
of your own home, except blood tests, we send you to
a lab to have your blood drawn for these. After you
pay for the test we mail you the kit, the results take
two weeks, the test results will be mailed to us and
we will call you to go over the results, its that easy!
All tests include the consultation for the report of
Click on test of interest on the right for more information
Call our office for details.
800-956-7083 OR 818-707-3126