The awareness of Helicobacter
pylori in gastrointestinal diseases has
increased greatly since Marshall and Warren
described the presence of Campylobacter-like
organisms in the antral mucosa of patients
with histological evidence of antrum gastritis
and peptic ulcers, especially duodenal
ulcers. The strong correlation between
the presence of H. pylori and histologically
confirmed gastritis, peptic ulcer disease
and gastric carcinoma, as well as disease
resolution after H. pylori eradication,
indicates a causative relationship.
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The ecological niche in humans
appears to be restricted to the stomach and duodenum.
Patients who harbor the organism are divided
into two basic groups: a) colonized and b) infected. Patients
who test positive for H. pylori yet have no signs
or symptoms of gastrointestinal disease are considered “colonized”.
Patients who test positive for H. pylori and present
with signs or symptoms of gastrointestinal disease
are considered “infected”. The
process by which a colonized individual becomes
infected remains unclear. The process
by which patients become colonized is also still
under investigation. Direct detection requires
that an invasive biopsy be taken from the upper
gastrointestinal tract. The presence of H. pylori
is then confirmed by direct microscopic examination,
rapid urease testing or culturing of the organism
from the biopsy material. This strategy
has the advantage of being able to detect active
infections while being highly specific with a
very high positive predictive value.
The invasive approach subjects the patient to
unnecessary risk and discomfort.
In contrast, Doctor’s Data,
Inc. offers the non-invasive HpSA enzyme immunoassay
(EIA), an in vitro qualitative procedure for
the detection of H. pylori antigens in human
stool. Test results can be used to diagnose
H. pylori infection, and to monitor patient response
during and post-therapy. Current scientific
literature indicates that testing to confirm
eradication should be performed at least four
weeks after the completion of therapy.
lab tests can be done through the mail in the privacy
of your own home, except blood tests, we send
you to a lab to have your blood drawn for these.
After you pay for the test we mail you the kit,
the results take two weeks, the test results will
be mailed to us and we will call you to go over
the results, its that easy! All tests include
the consultation for the report of findings. Click
on test of interest on the left for more information.
Call our office for more details: 800-956-7083 OR