The Many Faces of Arthritis - Arthritis Natural Pain Relief
by Teresa Rispoli, PhD.

There can be several factors at the root of Arthritis pain, causing both Osteo arthritis and Rheumatoid arthritis pain.

The most important cause of arthritis pain is a body that is too acid. Other factors leading up to arthritis pain can be nutritional deficiencies such as folic acid, EFA's, B6, B12, amino acid deficiencies of cysteine, glutathione, and taurine, as well as inflammation and elevated CRP, oxidative stress, pathogens such as Helicobacter Pylori or Chlamydia pneumonia and overuse of NSAIDS which can lead to Leaky Gut.

I can help you determine what is at the root of your Arthritis pain, by ascertaining which test to perform, and putting you on a comprehensive nutritional program to restore balance in your body, reduce the effects of stress and relieve your pain!

Osteo-Arthritis can be caused by a pH imbalance, especially when your body's pH is to acid from eating acid forming foods or too much stress. Stress causes the body to become acid. In order to buffer the acid the body leaches out the buffering minerals which buffer the acids; such as calcium, magnesium, potassium and chloride. What happens is the calcium, etc. becomes bio-unavailable and precipitates into the soft tissue causing calcium build-up in the joint and soft tissue (muscles and connective tissue). Chloride is needed to make hydrochloride (stomach acid). So digestion is hampered and no matter how much calcium and other minerals you take, if your HCL is low you will not be able to digest them. Potassium and magnesium are needed for relaxation of muscles, without the proper balance the body become stiff, you may get leg cramps or the heart beats too rapidly. In cases where the pH is to acid I recommend taking Orac Energy Greens daily
Click on product for more info). Greens raise your pH level to become more alkaline.

The most common type of arthritis is osteo arthritis (also known as degenerative joint disease) and strikes over 16 million Americans. It is a major cause of disability among older individuals. Typically osteo arthritis presents as pain, stiffness, or swelling in joints such as the hip, hand, and knee or spine, but it may affect other joints as well. Women run a higher risk of developing osteo arthritis than men, and other risk factors include heredity, excess weight, joint injury, and hormonal imbalances.

Although many people associate osteo arthritis with the "natural" wear and tear of joint cartilage, there are actually a variety of physiological factors that play an important role in the prevention, monitoring, and treatment of this condition. When there is wear and tear I recommend Glucosamine Chondroitin 1500/1200 daily. Click here for more info. This product aids in buildin back the joint and cartilage tissue.

I strongly emphasized the importance of working to undo actual degenerative mechanisms in the body rather than simply treating symptoms with anti-inflammatory drugs or analgesics.

Many studies show that nutritional deficiencies are a causative factor and both inflammation and oxidative stress are believed to be at the root of degenerative mechanisms in the development and progression of osteo arthritis (see info under Oxidative Stress Analysis , Essential and Metabolic Fatty Acids, and Cardiovascular Assessment).

Amino acids, which serve as the body's building blocks for protein, can impact both of these processes. Three amino acids are critical to antioxidant, anti-inflammatory functions: cysteine, glutathione, and taurine.

Cysteine influences the synthesis of the antioxidant glutathione (GSH), which is thought to play an important role in the inflammatory response by influencing the production of phagocytes.

Taurine acts as a specific scavenger for the hypochlorite ion, a free radical, and adequate levels naturally limit the degree of inflammation. When taurine is low, the inflammatory response is enhanced, commonly resulting in free radical reactions.

Other amino acid imbalances may also impact the etiology of osteo arthritis--particularly methionine metabolism. Normally, B12 and folate are necessary for the body to metabolize homocysteine to methionine, the essential amino acid the body needs to produce S-adenosylmethionine.

Numerous clinical trials have shown that S-adenosylmethionine can greatly reduce degenerative damage and symptoms of osteo arthritis in some patients, including related depression. Supplementation with folic Acid has also been shown to produce positive clinical results.

Along with S-adenosylmethionine, glucosamine has also been cited for its clinical ability to promote production of cartilage tissue and improve many symptoms of osteoarthritis. The body depends on glutamine as a metabolic source for the production of glucosamine.

Imbalances of amino acids may also signal key deficiencies of vitamins and minerals integral to the musculoskeletal system. Experimental studies show that impaired cartilage structure can be induced by a vitamin B6 deficiency. Vitamin B6 triggers the transformation of the amino acid homocysteine to cystathionine and then to cysteine and its urinary metabolites.

Amino Acids Analysis provides a precise measurement of over 40 analytes in plasma or urine. Test results come with report commentary, Interpretive Guidelines, and Interpretation-At-A-Glance for a clear and accurate assessment of each patient's unique nutritional needs.

Fatty acid imbalances are commonly seen in patients with chronic inflammatory conditions such as arthritis. While there can be many causes of inflammation, the final common mediators of cellular inflammation and cellular invasion are always chemical. These mediators include cytokines, leukotrienes, and eicosanoids, whose production is greatly impacted by levels of fatty acids in the body.

Examination of patients with cartilage degradation in osteoarthritis has linked increased severity of lesions with a higher proportion of arachidonic acid, an omega-6 fatty acid which shifts production toward more inflammatory prostaglandin's, leukotrienes, and thromboxanes.
1 In fact, two of these local hormones, prostaglandin's E2 and leukotrienes B4, are considered the primary mediators of inflammation in arthritis, modulated not only by fatty acid balance but by other factors such as treatment with mud pack therapy or consumption of ginger.2-4

Changes in the Western diet during this Century have resulted in increasing consumption of omega-6 oils, including arachidonic acid, with decreasing consumption of omega-3 oils. The net result of this dietary change has been a dramatic imbalance in fatty acid metabolism--causing a shift in production toward more pro-inflammatory eicosanoid hormones. These arachidonic acid metabolites play an integral role in the pathophysiology of osteoarthritis.

The Essential and Metabolic Fatty Acids Analysis can identify high levels of arachidonic acid and other fatty acid imbalances promoting a heightened inflammatory response in arthritis, arteriosclerosis, eczema, irritable bowel disease, and many other disorders.

Inflammation plays a pivotal role in the metabolic dysfunctions that trigger heart disease, and C-reactive protein is a specific marker that gauges the effect of this systemic inflammation on the body. Recent evidence has found increased levels of C-reactive protein in patients with early knee osteoarthritis. Researchers noted that "high levels of C-reactive protein predict those whose disease will progress over 4 years, suggesting that low-grade inflammation may be a significant aspect of early osteoarthritis and may be amenable to therapeutic intervention and secondary prevention."

High levels of C-reactive protein can also be triggered by previous infection with pathogens such as Helicobacter pylori or Chlamydia pneumonia.

To reduce inflammation OxiCell can be rubbed on top of inflamed areas. To reduce CRP and elevated homocysteine I have used FoloPro by Metagenics.

To test if you have Helicobacter pylori or Chlamydia pneumonia. You can take The Laboratory Test for Helicobacter pylori. Click on test for more info.

The Comprehensive Cardiovascular Assessment measures the most advanced independent biomarkers' for heart disease, including C-reactive protein, homocysteine, and Lp(a), along with all the classic lipids, two computed ratios, and an overall cardiac index.

In addition, symptoms of osteoarthritis are frequently treated with nonsteroidal inflammatory drugs (NSAIDS), but chronic use of these drugs can cause serious damage to the gastrointestinal (GI) system. An abundance of literature clearly delineates the causative role of these medications in triggering dyspepsia, ulcers, lesions, and other problems.
Increased permeability known as "Leaky Gut"and inflammation are also associated with chronic NSAID use.

Once the intestinal mucosa is damaged, bacteria, toxins, and allergens normally prevented from penetrating the GI system can permeate into the bloodstream, where they are carried into all parts of the body, both triggering and exacerbating symptoms and allergies.

One study of osteoarthritis patients taking NSAIDS found that over 50% exhibited at least one type of gastroduodenal damage.
Another study found an even higher rate--68%--and concluded that "fairly severe gastroduodenal injury occurs in asymptomatic patients with rheumatoid and osteoarthritis". Most importantly, these researchers also noted that symptoms do not necessarily predict the degree of GI tract damage.

I have personally used Permeability Factors, Repair Vite , and Glutathione Recycler to heal my own gut permeability. What a difference it made in reducing the pain! Click on product for more info.

Because endoscopy is a costly and invasive procedure, clinicians have recommended using non-invasive Intestinal Permeability Assessment to first identify patients who may benefit from further analysis, as well as to monitor response to treatment.
Click on test for more info.

The Intestinal Permeability Assessment is a non-invasive lactulose-mannitol challenge that provides crucial information about the integrity of the intestinal mucosa.

In summary, there can be several causative factors involved with Arthritis. Acid pH, nutritional deficiencies such as folic acid, EFA's B6, B12, amino acid deficiency of cysteine, glutathione, and taurine, inflammation and elevated CRP, oxidative stress, pathogens such as Helicobacter Pylori or Chlamydia pneumonia and over use of NSAIDS which can lead to Leaky Gut.

I can help you determine what is at the root of your Arthritis, by ascertaining which test to perform, several were mentioned above, and putting you on a comprehensive nutritional program to restore balance in your body, reduce the effects of stress and relieve your pain!

Schedule your Wellness Consultation today with Dr. Rispoli

Yours For Inner Health and Outer Beauty,

Teresa Rispoli, Ph.D., L.Ac.

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