Product Name: Progensa Plus
3 oz cream
Natural Progesterone Transdermal Replacement Creme With Phytoestrogen 20 mg Dose.
1 Full pump daily: rotate areas; face; stomach; arms; legs.
Full Description:

Each 3 oz. container of Progensa Plus contains an average 480 mg. per ounce of Natural Progesterone USP grade. Progensa cream is made from natural ingredients (no fragrances used). It is non-oily, does not leave a residue on the skin, and it has extremely effective absorption qualities. Under normal usage, the 3 oz. container will last two months or more.

Progensa Plus is slightly different than progesterone cream alone in that the phytoestrogens (ginseng extract and burdock root) which are the "Plus" in Progensa Plus actually help a little more with hot flashes than progesterone cream alone.

If you are looking for a progesterone only cream without an phytoestrogens in it, check out our companion product, Progensa 20 Natural Progesterone Cream.

Progensa Plus contains all natural ingredients, including, grape seed extract (a natural preservative), aloe vera, vitamin E and primrose oil all enhance the performance of natural progesterone when it is applied to the skin. The Progensa cream is sealed in an airtight clinical hygienic pump to protect the cream from losing its potency. This unique airtight pump container protects the ingredients in Progensa from oxidation and ensures the potency of the natural progesterone.

Most pharmaceutical grade progesterone is made from diogensin found in wild yams. Diosgenin is found in other plants as well but not in amounts significant enough to be of value. Diosgenin is converted into natural progesterone scientifically. There are no enzymes in the human body that will convert diosgenin, which is the active component of wild yams into progesterone. You can eat or rub on your skin all of the wild yam extract you like but the body will not convert it to progesterone. Diosgenin is still very useful in the body, however, and has been used by phytotherapists for centuries as an adaptagen. Whatever the effects of wild yam, it does not have the same benefits as natural progesterone.

Many companies sell wild yam products containing diosgenin stating that they provide the same benefits as progesterone. It is also added to many genuine progesterone creams in which it is usually identified as "wild yam extract". However there is usually not enough diosgenin in these creams to have much of an effect. Thus, many women using a wild yam cream have stated that they just don't seem to feel any change. Most of the research that has been done on progesterone demonstrates that it is supplemental natural progesterone that will produce an increase in saliva and serum levels of progesterone, not yam extract.

There has been considerable "hype" about all of the potential health benefits of progesterone cream applied to the skin. Here is what the medical scientific studies using randomized clinical trials show:

Hot flashes have been shown to be significantly improved by use of progesterone cream but osteoporosis may not be prevented at doses commonly used
(1)If you are taking estrogen replacement after the menopause, progesterone cream does not protect the uterine lining (endometrium) from risk of cancer.
(2)Progesterone is definitely absorbed into the blood stream by skin cream applications but blood level and saliva measurement of progesterone is not reliable due to the variable levels absorbed. Saliva levels are much higher than blood levels
(3, 4)Who should use progesterone topical skin cream?
(Dr. Rick Jelovsek's recommendations)
Women who have had a hysterectomy and have undergone natural or surgical menopause who do not wish to take estrogen replacement but who are having problems with hot flashes
Women who have not had the uterus removed but have undergone natural menopause and do not wish to take any estrogen replacement Women who are perimenopausal who are not taking prescription estrogens or birth control pills but who are having hot flashes and wish some relief.
All women who use topical skin progesterone cream should still take supplemental calcium (1000-1500 mg a day) to help prevent osteoporosis.

How to use

Each push of the pump dispenses approximately 20 mg of progesterone. The studies on hot flashes showed significant reduction at 20 mg a day. Therefore the dose each day should be the cream from one push of the pump rubbed on the skin. Dr. Jelovsek recommends using the cream on a daily basis rather than cyclical use as recommended by others.


Progensa Plus natural progesterone cream for women is easily and quickly absorbed into the body so you can apply it almost anywhere with success.

We recommend that you rotate the areas you apply it, to avoid saturating any one area. It is best absorbed where the skin is relatively thin and well supplied with capillary blood flow, such as the face, neck, upper chest, breasts, inner arms and inner thighs and wrists.

Apply and massage into your skin until it is noticeably absorbed. Natural progesterone cream should not be applied over top of other body creams or perfumes as this may interfere with proper absorption.

Progensa Plus is manufactured by AllVia Integrative Pharmaceuticals, Inc, Phoenix, Arizona, USA.

* This product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts:

Deionized Water, Aloe Vera Gel, Vegetable Glycerin, Caprylic/Capric Triglyceride, Sunflower Seed Oil, Shea Butter, Stearic Acid, Natural Progesterone USP, Isopropyl Palmitate, Stearyl Alcohol, PEG-100 Stearate, Glyceryl Stearate, Burdock Root, Ginseng, Dong Quai Extract, B-Sistosterol, Polyacrylamide and C13-C14 Isoparaffin and Laureth-7, Tocotrienol (Natural Super Vitamin E), TEA, Disodium EDTA, Methylparaben, Propyl Paraben, Diazolidinyl Ulrea, Lecithin, Carbomer, Chamomile, MSM, Evening Primose (Oenothera biennis) Oil

Menstruating Women:
Apply once a day at bedtime on days 12 through 27 of your cycle or as recommended by your physician.

Menopausal and Post-Menopausal Women:
Apply once a day at bedtime for 25 consecutive days followed by a five-day break or as recommended by your physician.

Each full pump dispenses 20mg of natural, bio-identical progesterone. Rotate the area of application between chest, abdomen, inner arms and thighs.